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2-Hydroxyethyl Methacrylate

CAS 868-77-9
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-Hydroxyethyl Methacrylate is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

2-Hydroxyethyl methacrylate (HEMA) is one of the most frequently reported contact allergens in the EU, particularly associated with artificial nail products. It is listed in EU Annex III (restricted substances) for nail care products with specific concentration limits. The compound readily penetrates imperfect nail barriers and skin, leading to sensitization in nail technicians and consumers. ECHA classifies it with H317 (skin sensitizer) and H319 (eye irritant).

Known concerns

  • Documented contact allergen (ECHA H317)
  • Nail product sensitization epidemic in EU
  • Eye irritation (H319)
  • Skin irritation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.