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Restricted quinoline fragrance

2-ISOBUTYLQUINOLINE

CAS 93-19-6
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

2-Isobutylquinoline is a leathery-smelling fragrance intermediate derived from quinoline. Concerns about genotoxicity and the absence of a supportive SCCS opinion place it firmly in the red tier.

Skin benefits

  • Used industrially as a fragrance and flavour intermediate with leathery notes
  • Has functioned historically as a chemical building block in dye synthesis

Known concerns

  • Quinoline parent compound classified by IARC as possibly carcinogenic to humans
  • Suspected genotoxic and mutagenic activity in mammalian cell assays
  • Potential skin sensitiser based on structural alerts
  • Not supported by SCCS safety opinion for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.