(2-Isopropylpent-4-enoyl)urea (apronalide)
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A urea derivative (apronalide) with mild acute toxicity but limited overall hazard data, used primarily as a sedative and not typically in cosmetics.
(2-Isopropylpent-4-enoyl)urea (apronalide) is a ureide compound that is primarily known as a sedative/hypnotic drug (non-barbiturate). It carries only H302 (acute toxicity) as a classified hazard. It is not listed in EU cosmetic regulation Annexes, meaning it has no formal restriction, but its pharmaceutical background suggests limited use in cosmetics. The unsaturated acyl group could contribute to reactivity. The overall hazard profile is relatively favorable compared to many ingredients in this batch.
Known concerns
- Limited cosmetic application data
- Drug compound background
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.