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2-METHOXYMETHOXY-P-PHENYLENEDIAMINE

50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-Methoxymethoxy-P-Phenylenediamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This hair dye intermediate features a methoxymethoxy (-O-CH2-O-CH3) ether acetal substituent on the p-phenylenediamine aromatic ring. It functions as a primary intermediate in oxidative hair color systems, similar to other alkylether-substituted PPD derivatives. The methoxymethoxy group provides improved solubility and modified coupling kinetics compared to simpler PPD derivatives. EU Annex III listing imposes specific concentration limits and mandatory sensitization labelling in accordance with Regulation (EC) No 1223/2009 Article 19.

Known concerns

  • Skin sensitizer - aromatic amine hair dye class
  • EU Annex III restricted - concentration limits apply
  • Required sensitization labelling

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.