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2-methylimidazole

CAS 693-98-1
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-methylimidazole is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

2-Methylimidazole is a heterocyclic compound functioning as an intermediate in chemical synthesis and industrial applications. It is not listed in EU Annexes II or III for cosmetics specifically. Studies have documented organ toxicity and endocrine-disrupting potential for imidazole derivatives at higher doses, raising concern for cosmetic use. The compound is also a known precursor in the synthesis of certain pharmaceuticals and dyes. While not directly restricted in cosmetics, the hazard profile and limited data supporting safe cosmetic use make it a ingredient of concern.

Known concerns

  • Documented organ toxicity in animal studies
  • Potential endocrine-disrupting activity
  • Limited data supporting safe cosmetic use
  • Not specifically evaluated by SCCS for cosmetic applications

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.