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2-METHYLPROPANOL

CAS 78-83-1
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A branched-chain primary aliphatic alcohol (isobutanol) used primarily as a solvent and fragrance ingredient; it has lower volatility and slower metabolism than the n-isomer but still carries mild irritation potential.

2-Methylpropanol (isobutanol) is a branched-chain C4 aliphatic alcohol used as a solvent in cosmetic formulations and as a fragrance ingredient. It has a characteristic sweet, musty odor. The branched structure reduces its volatility and skin penetration rate compared to n-butanol. It is listed in EU CosIng and is not specifically restricted in cosmetic regulations.

Skin benefits

  • Used as a solvent to help dissolve fragrance and other cosmetic ingredients
  • Provides mild musty-sweet odor as a fragrance ingredient

Known concerns

  • Mild skin and eye irritant at high concentrations
  • Volatile organic compound with indoor air quality concerns in confined spaces
  • Narcotic effects at high vapor concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.