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2-NAPHTHOL

CAS 135-19-3
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A naphthalene derivative used historically as an antiseptic but now restricted in EU cosmetics under Annex II/241 due to toxicological concerns.

2-Naphthol (beta-naphthol) is a naphthalene derivative listed in EU Cosmetics Regulation Annex II (List of substances which must not form part of the composition of cosmetic products) under reference II/241. This listing restricts its use in cosmetic products. 2-Naphthol has been associated with genotoxicity concerns and was historically used as an antiseptic in cosmetic products but was restricted due to evidence of potential for sensitization and systemic toxicity. The restriction under Annex II represents a complete prohibition for cosmetic use in the European Union.

Known concerns

  • EU Annex II/241 - prohibited in cosmetic products
  • Genotoxicity concerns from naphthalene structure
  • Skin sensitization potential
  • Historical concerns about systemic absorption and toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.