2-Nitropropane
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
2-Nitropropane is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
2-Nitropropane is a nitroparaffin solvent classified by IARC as Group 2B (possibly carcinogenic to humans) and known to cause liver toxicity in occupational exposure studies. It is not listed in EU Annexes II or III with a specific restriction, but its known carcinogenic potential makes it incompatible with the safety requirements of EU Cosmetics Regulation 1223/2009, which prohibits substances classified as carcinogenic, mutagenic, or toxic to reproduction (CMR) in Category 1A, 1B, or 2 from cosmetic products unless thoroughly evaluated and permitted. The use of 2-nitropropane in cosmetics would be extremely limited or prohibited based on its hazard profile.
Known concerns
- IARC Group 2B possible carcinogen
- Hepatotoxic in occupational exposure studies
- Prohibited or severely restricted in EU cosmetics due to CMR classification
- Acute toxicity by inhalation and ingestion
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.