2-Nitrotoluene
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
2-Nitrotoluene is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
2-Nitrotoluene is an aromatic nitro compound used primarily as a chemical intermediate in dye and pesticide synthesis. It carries concern under EU Cosmetics Regulation due to its structural relationship to known carcinogenic aromatic nitro compounds. It is not specifically listed in EU Annexes II or III with concentration limits, but substances with structural alerts for genotoxicity and carcinogenicity face significant scrutiny. The compound has been evaluated for mutagenicity and carcinogenicity in animal studies, showing some evidence of carcinogenic activity. Its use in cosmetics would be extremely restricted based on the precautionary principles of Regulation 1223/2009.
Known concerns
- Structural alerts for mutagenicity and carcinogenicity
- Animal studies show some evidence of carcinogenic activity
- Use in cosmetics extremely restricted under precautionary principle
- Not permitted in leave-on cosmetic products
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.