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2-SEC-BUTYLCYCLOHEXANONE

CAS 14765-30-1
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A secondary ketone fragrance with a characteristic minty-camphoraceous odor used in perfume compositions as a modifier; the branched sec-butyl substituent reduces skin penetration compared to linear analogs.

2-sec-Butylcyclohexanone is a substituted cyclohexanone with a characteristic minty, slightly camphoraceous, and herbaceous odor. The branched sec-butyl group reduces the compound's skin permeability relative to linear ketone analogs. However, cyclic ketones in general can be mild irritants, and specific safety data for this compound are limited.

Skin benefits

  • Provides minty-herbaceous fragrance notes with good substantivity
  • Used as a fragrance modifier to add complexity to herbal and fougere compositions

Known concerns

  • Mild skin irritation potential at high concentrations
  • Limited specific toxicological data available
  • May contribute to overall fragrance allergen load

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.