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2-T-BUTYLCYCLOHEXANOL

CAS 13491-79-7
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-T-Butylcyclohexanol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

2-t-Butylcyclohexanol (also known as 2-tert-butylcyclohexanol) is a hydrogenated aromatic alcohol that functions as a fragrance ingredient and masking agent in cosmetic formulations. It is known to act on the TRPV1 (capsaicin) receptor to produce a mild cooling sensation. The substance appears in CosIng without specific restrictions but is subject to the general fragrance allergen labelling requirements under EU Regulation 1223/2009 Annex III. Available repeated-dose toxicity data are adequate for a favourable safety assessment at current cosmetic use levels, and the compound has low acute toxicity.

Skin benefits

  • Provides a mild cooling sensory effect via TRPV1 receptor activation
  • Functions as a fragrance and masking ingredient

Known concerns

  • Fragrance allergen requiring labelling under EU Annex III (if above threshold)
  • May cause skin sensitisation in predisposed individuals
  • Limited data compared to better-studied cosmetic alcohols

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.