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2-TERT-BUTYL-P-CRESOL

CAS 2409-55-4
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Tert-Butyl-P-Cresol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

2-tert-Butyl-p-cresol (also called 2-tert-butyl-4-methylphenol or butyl cresol) is a hindered phenolic compound used as an antioxidant and fragrance ingredient in cosmetics. Under EU REACH and cosmetic regulations, it falls under scrutiny for skin sensitization potential (H317 may occur in some individuals) and environmental hazard classification. The tertiary butyl substitution at the ortho position reduces some phenolic reactivity but creates a distinct toxicological profile from simple cresols. The SCCS notes phenolic antioxidants for cumulative exposure concerns when used in multiple product categories.

Skin benefits

  • Antioxidant properties help protect cosmetic formulations from Rancimat
  • May provide mild UV-absorbing capacity in certain formulations

Known concerns

  • Skin sensitization potential in some individuals
  • Environmental hazard classification (aquatic toxicity concerns)
  • Cumulative exposure concern when used across multiple product types
  • Structural alert for phenolic toxicity in REACH assessments

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.