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botanical-active

(20S)-PROTOPANAXADIOL

CAS 30636-90-9
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

20(S)-Protopanaxadiol is a ginseng saponin aglycone with antioxidant and anti-inflammatory properties. CIR has assessed Panax-derived ingredients as safe, though dermal absorption data is limited.

Skin benefits

  • Active ginseng saponin aglycone with antioxidant properties
  • CIR has assessed Panax-derived ingredients as safe in cosmetics
  • Studied for anti-inflammatory effects in skin
  • Plant-derived and vegan-compatible

Known concerns

  • Concentrated saponin may have higher activity than crude extract
  • Limited dermal absorption data per CIR review
  • Pharmacological activity overlaps with pharmaceutical research
  • Variability in source ginseng material

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.