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3-(1-Naphthyl)-4-hydroxycoumarin

CAS 39923-41-6
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

3-(1-Naphthyl)-4-hydroxycoumarin is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

This compound is structurally related to anticoagulant rodenticides and acts as a vitamin K antagonist, causing lethal haemorrhage in rodents. It is not approved for use in cosmetic products under EU Regulation 1223/2009 and is classified as a CMR (Carcinogenic, Mutagenic, or Reprotoxic) substance under EU CLP criteria.

Known concerns

  • Acute anticoagulant toxicity if ingested
  • CMR substance - not permitted in cosmetic products
  • EU Annex II banned substance

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.