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3-(2-Hydroxyethyl)-p- phenylenediammonium sulphate

CAS 93841-25-9
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hydroxyethyl)-p- phenylenediammonium sulphate is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

3-(2-Hydroxyethyl)-p-phenylenediammonium sulfate is a diamino-substituted aromatic hair dye intermediate carrying the GHS Danger signal word with multiple severe hazard classifications: H301 (toxic if swallowed), H317 (may cause allergic skin reaction), H373 (may cause organ effects through prolonged or repeated exposure), H411 (toxic to aquatic life with long-lasting effects), and H319 (serious eye irritation). The EU CosIng database lists aromatic diamine hair dye precursors under strict regulation, and this hydroxyethyl-substituted phenylenediammonium salt falls into a category the SCCS has identified as requiring careful risk-benefit assessment, particularly due to the combination of acute toxicity, sensitization, and organ toxicity concerns.

Skin benefits

  • Enables specialized tone development in oxidative hair dye systems
  • Used as a coupling intermediate for specific shade creation

Known concerns

  • Acute oral toxicity (H301 - Toxic if swallowed)
  • Skin sensitization (H317)
  • Organ toxicity from repeated exposure (H373)
  • Aquatic toxicity (H411)
  • Multiple EU regulatory alerts as a hazardous hair dye precursor
  • The combination of H301+H317+H373 in one compound is flagged by SCCS as high-concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.