3,4',5-Tribromosalicylanilide (Tribromsalan (INN))

15

Avoid

CAS Number: 87-10-5

About 3,4',5-Tribromosalicylanilide (Tribromsalan (INN))

3,4',5-Tribromosalicylanilide (Tribromsalan (INN)) is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Detailed Analysis

Tribromsalan (3,4',5-tribromosalicylanilide) is an antimicrobial agent listed in EU Annex II of Cosmetics Regulation 1223/2009 as a prohibited substance. The compound is toxic to aquatic organisms (H400, H410) and its use in wash-off products leads to environmental release. The antimicrobial mechanism has raised concerns about endocrine disruption and bacterial resistance. No cosmetic use is permitted in the EU market.

Known Concerns

  • ⚠ EU Annex II banned substance - prohibited in cosmetic products
  • ⚠ Toxic to aquatic environment (H400, H410)
  • ⚠ Antimicrobial agent withdrawn due to safety concerns

Safety Score

15

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.