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Antimicrobial (prohibited)

3,4',5-Tribromosalicylanilide (Tribromsalan (INN))

CAS 87-10-5
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Tribromsalan is a halogenated antimicrobial once used in soaps but banned in EU cosmetics. It caused widespread photoallergic dermatitis and persistent light reactivity, making it unsafe for skin contact.

Skin benefits

  • Historically used as antimicrobial agent in soaps
  • Effective against gram-positive bacteria

Known concerns

  • Banned in EU cosmetics under Regulation 1223/2009 Annex II
  • Known photoallergen causing severe skin reactions
  • Linked to outbreaks of persistent light reactivity
  • Cross-sensitization with other halogenated salicylanilides
  • Phototoxicity risk on sun-exposed skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.