3,4-Diaminobenzoic acid, when used as a substance in hair dye products

Other

35

Caution

CAS Number: 619-05-6

About 3,4-Diaminobenzoic acid, when used as a substance in hair dye products

An aromatic diamine used as a primary intermediate in oxidative hair dye formulations, subject to strict EU restrictions due to its sensitizing potential.

Detailed Analysis

3,4-Diaminobenzoic acid (CAS 619-05-6) is a primary aromatic amine used in oxidative hair dye systems. Primary aromatic amines in hair dyes are generally restricted under EU Annex III of Regulation 1223/2009 due to their potential to form carcinogenic aromatic amines through azo reduction. The EU prohibits hair dye substances containing芳香族伯アミン that are known sensitizers and potential carcinogens. In vivo mutagenicity data for this specific compound is limited, contributing to a conservative safety assessment.

Skin Benefits

  • Used as a hair dye intermediate in oxidative coloring formulations
  • Can produce permanent hair color when combined with couplers and oxidizers

Known Concerns

  • EU Annex III restricted hair dye substance — use conditions and purity requirements apply
  • Primary aromatic amine — potential to form carcinogenic azo cleavage products
  • Known skin sensitizer; requires patch testing and specific concentration limits
  • May cause allergic reactions in sensitized individuals

Safety Score

35

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.