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Fragrance

3,4-DIMETHYLCYCLOPENTANE-1,2-DIONE

CAS 13494-06-9
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A cyclotene-type diketone with caramel-maple-coffee aroma. FEMA GRAS with long food/flavor use; solid safety record.

3,4-Dimethylcyclopentane-1,2-dione (CAS 13494-06-9) is a cyclic alpha-diketone used in food flavor (caramel, maple, coffee notes) and fragrance. FEMA GRAS (3268); widely reviewed by food safety bodies. RIFM/IFRA evaluated for fragrance. Not on EU Annex II. Alpha-diketones are reactive with biological nucleophiles at high concentrations, but at food/fragrance use levels safety is well established.

Function

PERFUMING

Skin benefits

  • Caramel-maple-coffee aroma
  • Dual food/fragrance safety history

Known concerns

  • Alpha-diketone reactivity at high dose
  • Minor irritation neat

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.