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3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one

CAS 24545-86-6
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

This spiro-xanthene compound is a synthetic organic colorant bearing nitro groups (NO2) that contribute to its vivid color. The multiple hazard statements (H315, H319, H335) indicate irritation concerns across skin, eyes, and respiratory routes. The nitro-substituted xanthene structure requires careful EU evaluation for cosmetic colorant approval. Environmental toxicity concerns also apply given its synthetic nature.

Known concerns

  • H315: Skin irritation
  • H319: Eye irritation
  • H335: Respiratory irritation
  • Nitro-substituted colorant requires rigorous safety assessment
  • EU colorant approval required

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.