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Synthetic fragrance ingredient

3,7-DIMETHYL-OCTANENITRILE

CAS 40188-41-8
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

3,7-Dimethyl-octanenitrile is a synthetic fragrance nitrile used for citrus notes. It carries class concerns around potential cyanide release on metabolism and limited cosmetic-specific safety data.

Function

PERFUMING

Skin benefits

  • Synthetic fragrance nitrile providing citrus-like olfactory notes
  • Stable in finished formulations compared to aldehyde counterparts

Known concerns

  • Aliphatic nitriles can release toxic cyanide on metabolism
  • Limited IFRA or SCCS evaluation specifically for this isomer
  • Potential skin sensitization typical of fragrance materials
  • Insufficient public dermal absorption data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related synthetic fragrance ingredients

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.