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(3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone

CAS 66938-41-8
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

(3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

This substituted benzophenone ketone carries hazard classifications H341 (suspected of causing genetic defects), H400 (very toxic to aquatic life), and H410 (very toxic to aquatic life with long-lasting effects) under CLP Regulation. The presence of both a nitro group and a chloro substituent significantly increases toxicological concern. The compound is not listed in CosIng as an approved cosmetic ingredient and would require extensive safety evaluation before any cosmetic use. Its mutagenic potential (H341) is a primary red flag for dermal exposure risk.

Known concerns

  • H341 - suspected mutagen/genotoxic concern
  • H400/H410 - very toxic to aquatic environment
  • Nitro-chloro substitution pattern increases toxicity
  • Not approved for cosmetic use in EU

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.