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3-NITRO-4-AMINOPHENOXYETHANOL

CAS 50982-74-6
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A phenoxyethanol ether bearing a nitro group, restricted in the EU (Annex II/1250) due to skin sensitisation potential and used as an oxidative hair dye intermediate.

3-Nitro-4-aminophenoxyethanol is a nitro-substituted phenoxy compound functioning as an oxidative hair dye intermediate. It is listed in EU Annex II/1250, restricting its use in cosmetic products, and carries a skin sensitisation warning (H317). The nitro substituent raises concerns about potential reductive metabolism to allergenic or toxic intermediates. Its cosmetic use is therefore limited to hair dye applications under strict regulatory control.

Known concerns

  • EU Annex II restricted (II/1250)
  • Skin sensitisation hazard (H317)
  • Potential metabolic reduction of nitro group

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.