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3-PROPYLIDENEPHTHALIDE

CAS 17369-59-4
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A phthalide-type fragrance ingredient listed in EU Annex III with potential sensitizing properties that requires concentration limits.

3-Propylidenephthalide (also called 3-propylidene phthalide or 3-propylidene-1(3H)-isobenzofuranone) is listed in EU Annex III (ref III/175) under the Cosmetics Regulation. Phthalides are naturally occurring compounds in Apiaceae plants with a celery-like aroma. The Annex III listing indicates a need for concentration restrictions due to safety concerns, though specific limits are established during the authorization process. This compound is primarily used in fine fragrances rather than skincare.

Skin benefits

  • Used as a fragrance in luxury perfumery

Known concerns

  • EU Annex III listed (ref III/175)
  • Potential skin sensitizer
  • Specific concentration limits apply

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.