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Specialty aromatic sulfonamide

4,4'-Bis(N-carbamoyl-4-methylbenzenesulfonamide)diphenylmethane

CAS 151882-81-4
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A bis-tolylsulfonamide-methylenedianiline derivative with no cosmetic safety dossier. The methylenedianiline-related backbone triggers carcinogenicity structural alerts and it is not a recognized cosmetic.

Skin benefits

  • Specialty sulfonamide chemistry with potential industrial use as a polymer or coating additive
  • Structural design suggests utility as a high-thermal-stability intermediate

Known concerns

  • Bisphenyl methane sulfonamide class is not an established cosmetic ingredient family
  • No CIR or SCCS safety review identified for this specific molecule
  • Aromatic sulfonamides can carry sensitization and metabolic activation concerns warranting caution
  • Methylenedianiline-related core raises potential structural-alert concerns for carcinogenicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.