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4,4-Dimethyl-1,3-oxazolidine

CAS 51200-87-4
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

4,4-dimethyl-1,3-oxazolidine is a cosmetic ingredient. Exercise caution due to limited available safety data.

4,4-Dimethyl-1,3-oxazolidine (DMDMH) is a formaldehyde-releasing preservative used in cosmetic formulations. It carries H226 (flammable liquid), H302, H312, H315, H317 (skin sensitization), H318 (eye damage), H332. The EU Annex III listing restricts its maximum concentration to 0.1% in finished products. Formaldehyde-releasing preservatives are under ongoing safety review due to sensitization concerns and the classified nature of formaldehyde itself as a carcinogen.

Known concerns

  • Formaldehyde releaser
  • Skin sensitization potential (H317)
  • Eye damage concern (H318)
  • EU Annex III restriction (max 0.1%)
  • Formaldehyde classified as carcinogen (H351)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.