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4,4'-Methylenebis(2-ethylaniline)

CAS 19900-65-3
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A methylene-dianiline derivative with documented carcinogenic (H351) and reprotoxic potential, classified as a substance of very high concern under EU REACH.

4,4'-Methylenebis(2-ethylaniline) is an aromatic amine with a structure related to 4,4'-methylenedianiline (MDA), a known carcinogen. ECHA classifies it with H302 (harmful if swallowed), H351 (suspected carcinogen), and H400/H410 (aquatic toxicity). It is a SVHC candidate under EU REACH due to its carcinogenic and reprotoxic properties, making it categorically unsuitable for cosmetic applications.

Known concerns

  • Suspected carcinogen (H351)
  • SVHC under REACH
  • Harmful if swallowed (H302)
  • Highly toxic to aquatic life

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.