4,4'-Methylenebis(2-ethylaniline)
Avoid
CAS Number: 19900-65-3
About 4,4'-Methylenebis(2-ethylaniline)
A methylene-dianiline derivative with documented carcinogenic (H351) and reprotoxic potential, classified as a substance of very high concern under EU REACH.
Detailed Analysis
4,4'-Methylenebis(2-ethylaniline) is an aromatic amine with a structure related to 4,4'-methylenedianiline (MDA), a known carcinogen. ECHA classifies it with H302 (harmful if swallowed), H351 (suspected carcinogen), and H400/H410 (aquatic toxicity). It is a SVHC candidate under EU REACH due to its carcinogenic and reprotoxic properties, making it categorically unsuitable for cosmetic applications.
Known Concerns
- ⚠ Suspected carcinogen (H351)
- ⚠ SVHC under REACH
- ⚠ Harmful if swallowed (H302)
- ⚠ Highly toxic to aquatic life
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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