4,5-Diamino-1-(2- hydroxyethyl)-1H- pyrazole

52

Moderate

CAS Number: 155601-30-2

About 4,5-Diamino-1-(2- hydroxyethyl)-1H- pyrazole

4,5-Diamino-1-(2- hydroxyethyl)-1H- pyrazole is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Detailed Analysis

This pyrazole-based hair dye intermediate carries H317 (skin sensitisation), H318 (serious eye damage), and H411 (aquatic toxicity) hazard statements. Like other oxidative hair dye precursors, it is used in combination with hydrogen peroxide to develop colour in the hair shaft. The EU regulates hair dye intermediates under Annex III, and formulators must comply with specific conditions of use and purity requirements.

Skin Benefits

  • ✓ Enables oxidative hair coloration
  • ✓ Used in permanent and semi-permanent hair dye formulations

Known Concerns

  • ⚠ Skin sensitiser (H317)
  • ⚠ Serious eye damage risk (H318)
  • ⚠ Aquatic toxic (H411)
  • ⚠ Hair dye intermediate - restricted under EU Annex III

Safety Score

52

Moderate

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.