4-AMINO-3-NITROPHENOL
Other
Caution
CAS Number: 610-81-1
About 4-AMINO-3-NITROPHENOL
A hair dye intermediate — used to create reddish-brown shades. EU-restricted (Annex III/215) due to toxicity concerns including skin sensitization, irritation, and being harmful if swallowed.
Detailed Analysis
4-Amino-3-Nitrophenol (CAS 610-81-1) is a nitroaminophenol used as an oxidative and semi-permanent hair dye intermediate, producing reddish to brown shades. EU Annex III/215 restricts its use with specific concentration limits. GHS classifications include H302 (harmful if swallowed), H315 (skin irritant), H317 (skin sensitizer), H319 (eye irritant), and H335 (respiratory irritant). The SCCS has evaluated this ingredient multiple times and allows use only under specified conditions in oxidative and non-oxidative hair dye products. Must not be used with nitrosating agents due to potential nitrosamine formation.
What It Does
Skin Benefits
- ✓ None — this is a hair coloring agent, not a skin-care ingredient
Known Concerns
- ⚠ EU Annex III restricted (III/215)
- ⚠ Skin sensitizer (H317) — allergic contact dermatitis
- ⚠ Harmful if swallowed (H302)
- ⚠ Skin and eye irritant (H315, H319)
- ⚠ Respiratory irritant (H335)
- ⚠ Must not be mixed with nitrosating agents
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.