4-Aminobiphenyl hydrochloride

3

Avoid

CAS Number: 2113-61-3

About 4-Aminobiphenyl hydrochloride

4-Aminobiphenyl hydrochloride is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Detailed Analysis

4-Aminobiphenyl hydrochloride is the salt form of 4-aminobiphenyl (biphenyl-4-ylamine), which is classified as a Group 1 human carcinogen by IARC due to documented bladder cancer causation in occupationally exposed humans. The hydrochloride salt retains the same toxicological concerns as the parent base. Under EU Regulation 1223/2009 Annex II, 4-aminobiphenyl and its salts are prohibited for use in cosmetic products. The salt form has no cosmetic authorization regardless of the cosmetic product type.

Known Concerns

  • ⚠ EU Annex II banned CMR Category 1A substance
  • ⚠ Same carcinogenic concern as parent 4-aminobiphenyl
  • ⚠ Prohibited from all cosmetic product types in EU
  • ⚠ No safe cosmetic use permitted

Safety Score

3

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.