(4-Hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride

Other

12

Avoid

CAS Number: 81880-96-8

About (4-Hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride

A cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Detailed Analysis

(4-Hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride is a hydrazide derivative containing both a para-hydrazinophenyl group and a sulfonamide moiety. The para-hydrazinophenyl structural alert is associated with mutagenicity and contact sensitisation in aromatic amine chemistry. The hazard profile is severe: acute oral toxicity (H301), multiple irritation endpoints (H315, H319, H335), skin sensitisation (H317), mutagenicity (H341), specific organ toxicity (H372), and chronic aquatic toxicity (H400, H410). This compound has no established cosmetic use or EU safety assessment, and the hazard profile strongly contraindicates any skin application.

Known Concerns

  • H301: Toxic if swallowed
  • H315: Causes skin irritation
  • H317: May cause allergic skin reaction
  • H319: Causes serious eye irritation
  • H335: May cause respiratory irritation
  • H341: Suspected of causing genetic defects
  • H372: Causes damage to organs through prolonged or repeated exposure
  • H400/H410: Very toxic to aquatic life / with long-lasting effects

Safety Score

12

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.