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4-Isopropyl-m-cresol

CAS 3228-02-2
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Isopropyl-m-cresol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

4-Isopropyl-m-cresol (also called carvacrol isomer) is permitted in the EU only up to 0.1% maximum concentration as a restriction under Annex III of Regulation (EC) No 1223/2009. As a phenolic compound, it exhibits broad-spectrum antimicrobial activity but presents risks of skin sensitization, irritation, and environmental toxicity. Its use is carefully controlled in leave-on and rinse-off cosmetic formulations.

Skin benefits

  • Antimicrobial/preservative action at controlled concentrations

Known concerns

  • Skin sensitizer at concentrations above 0.1%
  • EU Annex III restricted — concentration limit strictly enforced
  • Environmental toxicity (aquatic hazard)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.