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Antioxidant

4'-METHOXYCHALCONE

CAS 959-23-9
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A methoxy-chalcone (a flavonoid building block). Used as antioxidant/skin-brightener. ECHA flags it as a Cat 2 skin and eye irritant; recent toxicology suggests possible sensitisation.

Function

ANTIOXIDANTBLEACHINGSKIN CONDITIONING

Skin benefits

  • Antioxidant chalcone
  • Skin-conditioning and brightening
  • Listed in CosIng

Known concerns

  • Skin and eye irritant (H315/H319) per ECHA
  • Possible skin sensitiser per recent in silico testing
  • Respiratory irritant (H335)
  • Equivocal in vitro chromosome data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.