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4-Nitrobiphenyl

CAS 92-93-3
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

4-Nitrobiphenyl is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

4-Nitrobiphenyl is a nitro-substituted biphenyl compound that has demonstrated carcinogenic activity in multiple animal species. The nitro group on the aromatic ring system is a key structural alert for carcinogenicity. Under EU Regulation 1223/2009, substances classified as CMR (Carcinogenic, Mutagenic, or Reprotoxic) Category 1A or 1B are prohibited for cosmetic use and listed in Annex II. 4-Nitrobiphenyl's toxicological profile is inconsistent with cosmetic ingredient safety requirements.

Known concerns

  • Established animal carcinogen
  • CMR Category concern - prohibited in EU cosmetics
  • Highly toxic by multiple exposure routes
  • Not authorized for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.