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4-Nitrosophenol

CAS 104-91-6
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A nitrosophenol compound of significant concern due to its nitroso group, raising genotoxicity and nitrosamine formation potential in cosmetic formulations.

4-Nitrosophenol contains both a phenolic hydroxyl group and a nitroso group at the para position, creating a compound of significant toxicological concern. The nitroso moiety raises concerns about nitrosamine formation, a class of compounds known to be carcinogenic. Under EU Regulation 1223/2009, this ingredient lacks authorization and would be considered prohibited due to the absence of a safety assessment supporting its use in cosmetics.

Known concerns

  • Potential for nitrosamine formation - carcinogenic concern
  • Not authorized in EU cosmetics
  • Genotoxic potential
  • Absence of safety data for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.