Other
4-tert.-Butyl-3-methoxy-2,6-dinitrotoluene (Musk ambrette)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic nitromusk fragrance compound banned in cosmetic products in the EU due to photosensitisation and potential neurotoxicity concerns.
Musk ambrette (4-tert-butyl-3-methoxy-2,6-dinitrotoluene) is listed in EU Annex II as a substance prohibited in cosmetic products due to photosensitisation risk — it can cause severe allergic skin reactions upon UV exposure. The compound also shows neurotoxic potential (H372) and reproductive toxicity concerns (H361f), and has been banned by IFRA. EU CosIng confirms its prohibition in all cosmetic categories.
Known concerns
- EU Annex II banned — prohibited in all cosmetic products
- Photosensitiser — causes allergic reactions on UV exposure (H372)
- Reproductive toxicity suspected (H361f)
- IFRA banned — no fragrance industry authorisation
- Neurotoxicity concern
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.