4-tert-Butylpyrocatechol
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A phenolic antioxidant used in cosmetic formulations with significant skin sensitization risk and EU restrictions on maximum concentration.
4-tert-Butylpyrocatechol (4-tert-butylcatechol, PTBC) is a substituted catechol (1,2-dihydroxybenzene) with a tert-butyl group. It is used as an antioxidant and stabilizer in cosmetic formulations, particularly in fragrance compounds and fatty materials prone to oxidation. The catechol structure makes it susceptible to air oxidation and contributes to its skin sensitization potential. EU regulatory assessment has identified it as requiring caution in formulation use.
Skin benefits
- Effective antioxidant - prevents cosmetic product rancidity
- Stabilizes fragrance compounds
- Extends shelf life of oil-based formulations
Known concerns
- Known skin sensitizer - can cause allergic contact dermatitis
- Strong irritant to eyes and respiratory tract
- EU regulated for concentration limits in cosmetic products
- May cause skin depigmentation with prolonged contact
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.