Oxidative hair dye coupler
5-AMINO-4-CHLORO-O-CRESOL
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
5-Amino-4-chloro-o-cresol is an oxidative hair dye coupler with notable sensitization and genotoxicity concerns. Use is tightly limited, and previously PPD-sensitized users may cross-react.
Skin benefits
- Oxidative hair dye coupler producing color shades
- Reacts with developers to form chromophores
Known concerns
- Aromatic amine with sensitization potential
- SCCS opinions flag genotoxicity concerns for similar couplers
- Strict concentration limits when allowed
- Cross-reactivity with PPD-sensitized consumers
- Patch testing recommended before use
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related oxidative hair dye couplers
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.