5-CYCLOHEXADECENONE

72

Good

CAS Number: 37609-25-9

About 5-CYCLOHEXADECENONE

5-CYCLOHEXADECENONE is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Detailed Analysis

5-Cyclohexadecenone is a macrocyclic enone structurally related to civetone, used as a fragrance ingredient providing warm, musky, and slightly animalic scent notes. It is not subject to restriction under EU Regulation 1223/2009 and has a clean safety profile in skin sensitisation testing at typical use levels. Its macrocyclic structure contributes to excellent substantivity on skin.

Skin Benefits

  • ✓ Provides warm, animalic musks fixative properties
  • ✓ Enhances fragrance substantivity on skin

Known Concerns

  • ⚠ Low concern at standard cosmetic fragrance use levels
  • ⚠ May require allergen declaration depending on source and IFRA classification

Safety Score

72

Good

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.