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Reactive ketone (non-cosmetic)

5-HEXEN-2-ONE

CAS 109-49-9
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Reactive unsaturated ketone with Michael acceptor structure used as a chemical intermediate. Not approved as a cosmetic ingredient and carries sensitization, irritation, and acute toxicity concerns.

Skin benefits

  • No accepted cosmetic benefit identified
  • Industrial intermediate in flavor and fragrance synthesis

Known concerns

  • Reactive enone with Michael acceptor structure, structural alert for sensitization and genotoxicity
  • Flammable and acutely toxic by inhalation
  • Not approved as a cosmetic ingredient in the EU
  • Skin and eye irritant in undiluted form

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.