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5-METHYL-2-PHENYL-2-HEXENAL

CAS 21834-92-4
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

5-methyl-2-phenyl-2-hexenal is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

This compound combines an alpha,beta-unsaturated aldehyde system with a phenyl substituent, creating a structurally potent sensitizer. The H317 classification confirms skin sensitization risk. Unsaturated aldehydes are well-documented contact allergens in EU dermatological literature, and the aromatic ring increases lipophilicity enhancing skin penetration. IFRA standards impose strict concentration limits on this class of fragrance materials in leave-on cosmetic products.

Known concerns

  • skin sensitizer (H317)
  • potential strong allergen
  • IFRA restricted

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.