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6-ETHYLIDENEOCTAHYDRO-5,8-METHANO-2H-1-BENZOPYRAN-2-ONE

CAS 69486-14-2
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lactone fragrance compound with a maximum concentration limit in EU cosmetic products.

This bicyclic lactone (coumarin derivative) carries H302 (acute oral toxicity) and H411 (aquatic toxicity). It is not specifically listed in EU cosmetic Annexes, meaning general safety assessment applies. Lactones in cosmetics can contribute to fragrance character but may also cause allergic reactions in sensitised individuals. PubChem safety score is 55.

Skin benefits

  • Fragrance with sweet, tonka-like character

Known concerns

  • Acute oral toxicity (H302)
  • Aquatic toxic (H411)
  • Potential skin sensitisation from lactones

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.