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Colorant

6-HYDROXYINDOLE

CAS 2380-86-1
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An oxidative hair-dye coupler. Produces deep tones when mixed with peroxide, but it's a known skin sensitizer — only allowed in regulated hair-dye products with patch tests.

Skin benefits

  • Oxidative hair-dye coupler
  • Produces dark shades when oxidized
  • Used in EU-permitted hair colorants

Known concerns

  • Skin sensitizer — patch testing required
  • SCCS reviewed; restricted to oxidative hair-dye use
  • H317 may cause allergic skin reaction
  • Not for direct skin or eyebrow/eyelash use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.