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Fragrance

6-ISOBUTYLQUINOLINE

CAS 68141-26-4
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An alkylated quinoline used for leather/animalic fragrance character. Quinoline class has carcinogenicity signals; scored with caution.

6-Isobutylquinoline (CAS 68141-26-4) is an alkylated heterocyclic aromatic amine used at trace levels in perfumery for animalic, leather, and tobacco accords. Quinoline class contains members with IARC Group 2B carcinogenicity (possibly carcinogenic to humans) and aromatic amine structural alerts. Public data on this specific isomer are limited. IFRA/RIFM govern use levels. Default-down applied.

Function

PERFUMING

Skin benefits

  • Animalic/leather perfumery note

Known concerns

  • Quinoline class carcinogenicity signals
  • Aromatic amine alerts
  • Thin public dossier
  • Photosensitization potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.