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Skin lipid / sterol

7-DEHYDROCHOLESTEROL

CAS 434-16-2
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A natural skin sterol and vitamin D precursor used in barrier-supporting skincare. It is biocompatible but its photochemistry on skin warrants thoughtful formulation and packaging.

Skin benefits

  • A natural precursor of vitamin D found in skin
  • Supports skin barrier lipid composition
  • Used in some formulations targeting barrier repair and dryness
  • Biocompatible with skin's native sterol chemistry

Known concerns

  • UV exposure converts it to pre-vitamin D and other photoproducts whose long-term topical implications are not fully characterized
  • Limited dedicated SCCS or CIR cosmetic review
  • Stability and oxidation can yield reactive sterol derivatives

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.