7-Methylcoumarin, when used as a fragrance ingredient
Other
Avoid
CAS Number: 2445-83-2
About 7-Methylcoumarin, when used as a fragrance ingredient
A synthetic coumarin fragrance banned in EU cosmetics. PubChem safety score of just 5 — associated with liver toxicity and phototoxicity concerns.
Detailed Analysis
7-Methylcoumarin is a substituted coumarin once used as a fragrance ingredient. It is banned in EU cosmetics under Annex II when used as a fragrance. PubChem assigns a safety score of only 5, reflecting serious toxicological concerns. Coumarins as a class can be hepatotoxic, and methylated variants may show enhanced toxicity. GHS codes include skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). The IFRA (International Fragrance Association) also restricts or prohibits its use. Coumarin derivatives can cause photodermatitis.
Known Concerns
- ⚠ EU banned as fragrance (Annex II)
- ⚠ PubChem safety score: 5
- ⚠ hepatotoxicity potential
- ⚠ phototoxicity concerns
- ⚠ IFRA restricted
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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