7-oxabicyclo[4.1.0]hept-3-ylmethyl 7-oxabicyclo[4.1.0]heptane-3-carboxylate

15

Avoid

CAS Number: 2386-87-0

About 7-oxabicyclo[4.1.0]hept-3-ylmethyl 7-oxabicyclo[4.1.0]heptane-3-carboxylate

A diepoxide carboxylate with extensive hazard warnings (H317, H341, H351, H373) including suspected carcinogenicity that precludes cosmetic use.

Detailed Analysis

This diepoxide compound (essentially two epoxidized cyclohexane rings connected by a methylene carboxylate linker) carries multiple critical hazard statements: H317 (skin sensitization), H341 (suspected mutagen), H351 (suspected carcinogen), H373 (organ effects), H336 (CNS effects), H402 (aquatic toxicity), H412 (aquatic toxicity). The presence of TWO epoxide rings dramatically increases the potential for protein reactivity and sensitization. The H351 and H341 classifications make this compound unsuitable for cosmetic applications under EU Regulation 1223/2009. The compound is an industrial chemical with no established safe use in personal care products.

Known Concerns

  • ⚠ H317 skin sensitization
  • ⚠ H341 suspected mutagen
  • ⚠ H351 suspected carcinogen
  • ⚠ H373 organ effects
  • ⚠ H336 CNS effects
  • ⚠ Diepoxide structural alert - extreme sensitization concern
  • ⚠ Likely prohibited in EU cosmetics

Safety Score

15

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.