8,18-Dichloro-5,15-diethyl-5,15-dihydrodiindolo[3,2-b:3',2'-m]triphenodioxazine
Other
Moderate
CAS Number: 6358-30-1
About 8,18-Dichloro-5,15-diethyl-5,15-dihydrodiindolo[3,2-b:3',2'-m]triphenodioxazine
A triphenodioxazine pigment used in hair dyes and decorative cosmetics, restricted to rinse-off products in the EU with limited long-term exposure safety data.
Detailed Analysis
8,18-Dichloro-5,15-diethyl-5,15-dihydrodiindolo[3,2-b:3',2'-m]triphenodioxazine (CAS 6358-30-1, PubChem CID 61387) is a triphenodioxazine violet pigment. It is listed in EU CosIng Annex IV as a colorant restricted to rinse-off cosmetic products. Triphenodioxazine pigments are chemically stable and used at low concentrations in hair dyes and cosmetic formulations. The restriction to rinse-off products reflects the EU's precautionary approach to colorants for which long-term leave-on exposure data are insufficient. The GHS hazard profile shows H400/H410 aquatic toxicity, contributing to the moderate-low safety score.
Known Concerns
- ⚠ Restricted to rinse-off products per EU CosIng Annex IV
- ⚠ Very toxic to aquatic life (H400, H410)
- ⚠ Insufficient leave-on safety data
Safety Score
Moderate
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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