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Acetamide

CAS 60-35-5
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A simple organic amide and solvent historically used in lacquers and as a chemical intermediate. It has limited cosmetic use and carries some health concerns.

Acetamide (CH3CONH2) is the amide of acetic acid. It functions as a solvent in industrial applications and has been used as a plasticizer and chemical intermediate. IARC has classified acetamide as Group 2B (possibly carcinogenic to humans). It may cause skin and eye irritation. While it has some use as a humectant in specialized cosmetic formulations, its carcinogenic potential limits its appeal. EU regulations restrict its use, and it appears on relevant regulatory lists for cosmetic restrictions.

Skin benefits

  • May function as a humectant at low concentrations
  • Limited cosmetic application

Known concerns

  • IARC Group 2B carcinogen (possibly carcinogenic to humans)
  • Skin and eye irritant
  • EU regulatory restrictions apply
  • Limited safety data for chronic topical exposure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.