Acetamide
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A simple organic amide and solvent historically used in lacquers and as a chemical intermediate. It has limited cosmetic use and carries some health concerns.
Acetamide (CH3CONH2) is the amide of acetic acid. It functions as a solvent in industrial applications and has been used as a plasticizer and chemical intermediate. IARC has classified acetamide as Group 2B (possibly carcinogenic to humans). It may cause skin and eye irritation. While it has some use as a humectant in specialized cosmetic formulations, its carcinogenic potential limits its appeal. EU regulations restrict its use, and it appears on relevant regulatory lists for cosmetic restrictions.
Skin benefits
- May function as a humectant at low concentrations
- Limited cosmetic application
Known concerns
- IARC Group 2B carcinogen (possibly carcinogenic to humans)
- Skin and eye irritant
- EU regulatory restrictions apply
- Limited safety data for chronic topical exposure
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.