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Fragrance

ACETANILID

CAS 103-84-4 Updated
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A simple aniline-derived amide once used as a fragrance fixative and as an early analgesic. Its aniline base raises real safety questions (methaemoglobinaemia, organ toxicity); largely retired from modern fragrance use.

Function

FRAGRANCEPERFUMING

Skin benefits

  • Historical use as a fragrance fixative
  • Stable aromatic amide

Known concerns

  • Aniline-derived structure raises hepato- and nephrotoxic concerns from past pharmaceutical use
  • Suspected methaemoglobinaemia precursor at higher exposure
  • Modern fragrance industry has largely retired this ingredient
  • Limited modern cosmetic safety justification

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.