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Synthetic acetylated peptide

ACETYL HEXAPEPTIDE-31

CAS -
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Acetyl hexapeptide-31 is a synthetic acetylated peptide used in anti-ageing skincare for claimed skin-smoothing effects. It is generally well tolerated, with efficacy data driven mainly by supplier studies.

Function

SKIN CONDITIONING

Skin benefits

  • Used for skin-smoothing and conditioning effects
  • Low irritation potential at typical use levels
  • Marketed for fine-line and elasticity support
  • Compatible with most leave-on formula bases

Known concerns

  • Limited independent clinical and safety data
  • Efficacy claims mainly from supplier studies
  • Penetration and bioavailability of peptides remain debated
  • No long-term cumulative-use evidence

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.